The best open-science alternatives

Kun

KunAgent/Kun

Local-first AI agent workspace for coding, writing, design, research, and automation — one runtime for desktop GUI and TUI.

Choose Kun if…

• you specifically need agentic-workflow or ai-assistant

Shares ai-agent, desktop-app, local-first, mcp with open-science.

nanoMuse

nano-muse/nanoMuse

nanoMuse: an open-source personal agent for every device you own. One agent with a name and a look of its own that does things, keeps working while the app is closed, remembers you, and asks before anything you cannot undo. On Android, iPhone and iPad, Windows / macOS / Linux and in the browser; your phone's screen and your computer as its hands.

Choose nanoMuse if…

• you would rather work in Swift than TypeScript
• GNU General Public License v3.0 suits your use better than Apache License 2.0
• you specifically need android or computer-use

Shares agent-skills, ai-agent, desktop-app, mcp with open-science.

skales

skalesapp/skales

Personal AI desktop agent for Windows, macOS, Linux, Android & iOS. Set a goal, it works on its own. Teams (pair two desktops, agents + humans), Agent2Agent, Workflows, Codework, multi-agent orgs, desktop + browser automation. 15+ AI providers, BYOK. No Docker, no terminal. Agent Skills (SKILL.md). Migration importer. Recurring autonomous tasks.

Choose skales if…

• you prefer a smaller, narrower project to a large one
• you specifically need agentic-ai or ai-assistant

Shares ai-agent, desktop-app, local-first, mcp with open-science.

cc-haha

NanmiCoder/cc-haha

Local-first cross-platform desktop workspace for Claude Code / agents: multi-agent, Git worktrees, code diffs, skill marketplace, multi-model, Computer Use, task-aware desktop pets, with WeChat, Feishu, DingTalk, Telegram, WhatsApp and H5 access.

Choose cc-haha if…

• MIT License suits your use better than Apache License 2.0
• you want the more widely starred option (15.4k)
• you specifically need agent or ai

Shares ai-agent, desktop-app, mcp with open-science.

claude-devtools

matt1398/claude-devtools

The missing DevTools for Claude Code — inspect session logs, tool calls, token usage, subagents, and context window in a visual UI. Free, open source.

Choose claude-devtools if…

• MIT License suits your use better than Apache License 2.0
• you specifically need ai or ai-debugging

Shares ai-agent, desktop-app, open-source with open-science.

PI-Desktop

vastsa/PI-Desktop

Local-first AI coding agent desktop: Electron + Rust host core + pi Agent Harness + user-installable plugins

Choose PI-Desktop if…

• GNU Lesser General Public License v3.0 suits your use better than Apache License 2.0
• you specifically need coding-agent or electron

Shares ai-agent, desktop-app, local-first, mcp with open-science.

editor

pascalorg/editor

Open-source 3D architectural editor with a local CLI, MCP tools, and practical workflows for humans and AI agents.

Choose editor if…

• MIT License suits your use better than Apache License 2.0
• you want the more widely starred option (25.5k)
• you specifically need 3d or ai-agents

Shares agent-skills, local-first, mcp with open-science.

autoclip

zhouxiaoka/autoclip

AutoClip｜一个链接，一键出片。开源 AI 视频剪辑桌面工具，将播客、访谈、课程等长视频自动剪成短视频，生成字幕、封面和发布文案，适配抖音、小红书、TikTok、Reels 与 YouTube Shorts。Open-source AI video clipping & content repurposing.

Choose autoclip if…

• you would rather work in Python than TypeScript
• MIT License suits your use better than Apache License 2.0
• you want the more widely starred option (10.4k)
• you specifically need ai-video-editor or content-repurposing

Shares ai-agent, desktop-app, mcp, open-source with open-science.

siyuan

siyuan-note/siyuan

An open-source, privacy-first, self-hosted knowledge workspace where humans and AI agents work together 开源、隐私优先、自托管的知识工作空间，让人与智能体在此协作

Choose siyuan if…

• GNU Affero General Public License v3.0 suits your use better than Apache License 2.0
• you want the more widely starred option (47.2k)
• you specifically need agentic-ai or knowledge-base

Shares ai-agent, local-first, mcp with open-science.

note-gen

codexu/note-gen

Capture first. Organize later. A local-first Markdown app that turns scattered records into clear notes with AI.

Choose note-gen if…

• GNU General Public License v3.0 suits your use better than Apache License 2.0
• you want the more widely starred option (13.0k)
• you specifically need agent or ai-notes

Shares local-first, mcp, open-source with open-science.

LobsterAI

netease-youdao/LobsterAI

Open-source, desktop-grade AI agent that gets real work done — data analysis, slides, docs, video & web research. Built on OpenClaw; runs tools on your real desktop and takes commands from your phone via WeChat, Feishu, DingTalk & Telegram.

Choose LobsterAI if…

• MIT License suits your use better than Apache License 2.0
• you specifically need agent or ai-assistant

Shares ai-agent, desktop-app, mcp with open-science.

agenta

Agenta-AI/agenta

Agenta is a workspace where you and your team build agents and automations.

Choose agenta if…

• you specifically need agent-builder or agent-observability

Shares ai-agent, mcp, open-source with open-science.