The best open-source Python AI projects in 2026

Last updated

Sep 11, 2026

Projects considered

257

Commits reviewed

0 of 257

Python libraries, frameworks and applications across the AI and developer-tooling catalog.

Mostly written in Python.

1. 1

   system-design-primer

   donnemartin/system-design-primer

   Learn how to design large-scale systems. Prep for the system design interview. Includes Anki flashcards.

   Pushed 2 months ago.OtherPythonDesign systems376.7k+882

   Save
2. 2

   hermes-agent

   NousResearch/hermes-agent

   The agent that grows with you

   Pushed today.MIT LicensePythonAgents260.1k+2.5k

   Save
3. 3

   AutoGPT

   Significant-Gravitas/AutoGPT

   AutoGPT is the vision of accessible AI for everyone, to use and to build on. Our mission is to provide the tools, so that you can focus on what matters.

   Pushed today.OtherPythonApps187.9k+100

   Save
4. 4

   skills

   anthropics/skills

   Public repository for Agent Skills

   Pushed 6 days ago.No license detectedPythonSkills187.0k+2.9k

   Save
5. 5

   transformers

   huggingface/transformers

   🤗 Transformers: the model-definition framework for state-of-the-art machine learning models in text, vision, audio, and multimodal models, for both inference and training.

   Pushed today.Apache License 2.0PythonDeveloper tools168.5k+255

   Save
6. 6

   stable-diffusion-webui

   AUTOMATIC1111/stable-diffusion-webuiSlowing

   Stable Diffusion web UI

   Last push 8 months ago.GNU Affero General Public License v3.0PythonApps165.2k+78

   Save
7. 7

   open-webui

   open-webui/open-webui

   User-friendly AI Interface (Supports Ollama, OpenAI API, ...)

   Pushed today.OtherPythonApps157.6k+727

   Save
8. 8

   langflow

   langflow-ai/langflow

   Langflow is a powerful tool for building and deploying AI-powered agents and workflows.

   Pushed yesterday.MIT LicensePythonAgents156.3k+224

   Save
9. 9

   langchain

   langchain-ai/langchain

   The agent engineering platform.

   Pushed yesterday.MIT LicensePythonAgents148.9k+391

   Save
10. 10

    spec-kit

    github/spec-kit

    💫 Toolkit to help you get started with Spec-Driven Development

    Pushed yesterday.MIT LicensePythonDeveloper tools146.3k+3.2k

    Save
11. 11

    ComfyUI

    Comfy-Org/ComfyUI

    The most powerful and modular diffusion model GUI, api and backend with a graph/nodes interface.

    Pushed today.GNU General Public License v3.0PythonApps144.8k+1.3k

    Save
12. 12

    ui-ux-pro-max-skill

    nextlevelbuilder/ui-ux-pro-max-skill

    An AI skill that provides design intelligence for building professional UI/UX across multiple platforms.

    Pushed yesterday.MIT LicensePythonSkills144.6k+3.3k

    Save
13. 13

    graphify

    Graphify-Labs/graphify

    Turn any codebase, with its docs, SQL schemas, configs, and PDFs, into a queryable knowledge graph. A /graphify skill for Claude Code, Cursor, Codex, and Gemini CLI: local deterministic AST parsing, every edge explained, no vector store.

    Pushed yesterday.Apache License 2.0PythonDeveloper tools141.6k+5.0k

    Save
14. 14

    MoneyPrinterTurbo

    harry0703/MoneyPrinterTurbo

    利用 AI 大模型和自动化工作流，根据主题或关键词一键生成高清短视频。Generate HD short videos from a topic or keyword with an automated AI workflow.

    Pushed yesterday.MIT LicensePythonApps138.0k+2.4k

    Save
15. 15

    TradingAgents

    TauricResearch/TradingAgents

    TradingAgents: Multi-Agents LLM Financial Trading Framework

    Pushed 8 days ago.Apache License 2.0PythonDeveloper tools120.2k+3.2k

    Save
16. 16

    browser-use

    browser-use/browser-use

    Agents that use the browser.

    Pushed 2 days ago.MIT LicensePythonAgents119.9k+662

    Save
17. 17

    Agent-Reach

    Panniantong/Agent-Reach

    Give your AI agent eyes to see the entire internet. Read & search Twitter, Reddit, YouTube, GitHub, Bilibili, XiaoHongShu — one CLI, zero API fees.

    Pushed 3 days ago.MIT LicensePythonDeveloper tools108.3k+3.8k

    Save
18. 18

    Deep-Live-Cam

    hacksider/Deep-Live-Cam

    real time face swap and one-click video deepfake with only a single image

    Pushed 8 days ago.GNU Affero General Public License v3.0PythonApps97.6k+283

    Save
19. 19

    vllm

    vllm-project/vllm

    A high-throughput and memory-efficient inference and serving engine for LLMs

    Pushed today.Apache License 2.0PythonDeveloper tools96.2k+542

    Save
20. 20

    Scrapling

    D4Vinci/Scrapling

    🕷️ An adaptive Web Scraping framework that handles everything from a single request to a full-scale crawl!

    Pushed yesterday.BSD 3-Clause "New" or "Revised" LicensePythonPlugins93.8k+3.9k

    Save
21. 21

    deer-flow

    bytedance/deer-flow

    An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.

    Pushed yesterday.MIT LicensePythonDeveloper tools84.9k+454

    Save
22. 22

    unsloth

    unslothai/unsloth

    Local UI to run and train LLMs and diffusion models. Supports GGUF, MLX, Qwen3.8, DeepSeek-V4, MiniMax-H3, Gemma 4, FLUX and more.

    Pushed today.Apache License 2.0PythonApps79.0k+386

    Save
23. 23

    headroom

    headroomlabs-ai/headroom

    Compress tool outputs, logs, files, and RAG chunks before they reach the LLM. 20% fewer tokens for coding agents, 60-95% fewer tokens for JSON, same answers. Library, proxy, MCP server.

    Pushed yesterday.Apache License 2.0PythonDeveloper tools78.7k+724

    Save
24. 24

    LlamaFactory

    hiyouga/LlamaFactory

    Unified Efficient Fine-Tuning of 100+ LLMs & VLMs (ACL 2024)

    Pushed yesterday.Apache License 2.0PythonDeveloper tools75.9k+126

    Save
25. 25

    OpenMontage

    calesthio/OpenMontage

    World's first open-source, agentic video production system. 12 production pipelines, 100+ tools, 700+ agent skill and production-knowledge files. Turn your AI coding assistant into a full video production studio.

    Pushed 6 days ago.GNU Affero General Public License v3.0PythonApps75.7k+3.4k

    Save
26. 26

    OpenBB

    OpenBB-finance/OpenBB

    Open Data Platform for analysts, quants and AI agents.

    Pushed 2 days ago.OtherPythonAgents75.0k+269

    Save
27. 27

    strix

    usestrix/strix

    Open-source AI penetration testing tool to find and fix your app’s vulnerabilities.

    Pushed yesterday.Apache License 2.0PythonApps73.5k+1.3k

    Save
28. 28

    ppt-master

    hugohe3/ppt-master

    AI turns documents or topics into real, native PowerPoint decks—with native shapes, transitions and animations, data-backed charts and tables on demand, audio narration from speaker notes, and support for your own .pptx templates. · by Hugo He

    Pushed yesterday.MIT LicensePythonApps73.0k+3.6k

    Save
29. 29

    MetaGPT

    FoundationAgents/MetaGPTSlowing

    🌟 The Multi-Agent Framework: First AI Software Company, Towards Natural Language Programming

    Last push 10 months ago.MIT LicensePythonDeveloper tools71.2k+116

    Save
30. 30

    docling

    docling-project/docling

    Get your documents ready for gen AI

    Pushed today.MIT LicensePythonApps70.1k+393

    Save
31. 31

    ai-job-search

    MadsLorentzen/ai-job-search

    The job search that runs on your machine. AI job application framework built on Claude Code: evaluate postings, tailor CVs, write cover letters, prep interviews. Fork it and own it.

    Pushed yesterday.MIT LicensePythonApps69.3k+2.7k

    Save
32. 32

    mem0

    mem0ai/mem0

    The Memory Layer for AI Agents - Drop-in memory infrastructure for AI agents and apps. Context that persists. Built for production.

    Pushed 4 days ago.Apache License 2.0PythonAgents68.3k+425

    Save
33. 33

    daily_stock_analysis

    ZhuLinsen/daily_stock_analysis

    LLM 驱动的多市场股票智能分析系统：多源行情、实时新闻、决策看板与自动推送，支持零成本定时运行。 LLM-powered multi-market stock analysis system with multi-source market data, real-time news, decision dashboard, automated notifications, and cost-free scheduled runs.

    Pushed yesterday.MIT LicensePythonApps67.5k+348

    Save
34. 34

    last30days-skill

    mvanhorn/last30days-skill

    AI agent skill that researches any topic across Reddit, X, YouTube, HN, Polymarket, and the web - then synthesizes a grounded summary

    Pushed today.MIT LicensePythonSkills66.4k+799

    Save
35. 35

    minimind

    jingyaogong/minimind

    🧠 Train a 64M-parameter LLM from scratch in just 2h!

    Pushed 8 days ago.Apache License 2.0PythonApps64.8k+341

    Save
36. 36

    humanizer

    blader/humanizerScanned · findings(2)

    Agent skill that removes signs of AI-generated writing from text

    Pushed 7 days ago.MIT LicensePythonSkills64.2k+3.0k

    Save
37. 37

    TrendRadar

    sansan0/TrendRadar

    ⭐AI-driven public opinion & trend monitor with multi-platform aggregation, RSS, and smart alerts.🎯 告别信息过载，你的 AI 舆情监控助手与热点筛选工具！聚合多平台热点 + RSS 订阅，支持关键词精准筛选。AI 智能筛选新闻 + AI 翻译 + AI 分析简报直推手机，也支持接入 MCP 架构，赋能 AI 自然语言对话分析、情感洞察与趋势预测等。支持 Docker ，数据本地/云端自持。集成微信/飞书/钉钉/Telegram/邮件/ntfy/bark/slack 等渠道智能推送。

    Pushed 6 days ago.GNU General Public License v3.0PythonPlugins63.4k+159

    Save
38. 38

    litellm

    BerriAI/litellm

    The fastest, litest AI Gateway. Rust core with Python SDK. Call 100+ LLM APIs in OpenAI (or native) format with cost tracking, guardrails, load balancing, and logging [Bedrock, Azure, OpenAI, Anthropic, OpenAI, VertexAI, vLLM, Nvidia NIM]

    Pushed today.OtherPythonDeveloper tools62.6k+482

    Save
39. 39

    autogen

    microsoft/autogen

    A programming framework for agentic AI

    Pushed 6 days ago.Creative Commons Attribution 4.0 InternationalPythonDeveloper tools61.7k+104

    Save
40. 40

    crewAI

    crewAIInc/crewAI

    Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.

    Pushed today.MIT LicensePythonDeveloper tools60.5k+286

    Save

Showing the top 40 of 257. Search the full catalog.